What is the answer to the NYT Crossword clue "Prefix with center" from April 21, 2026?

Crossword clue

“Prefix with center”

This clue appeared as 3-Down in the NYT Crossword on Tuesday, April 21, 2026. The answer has 3 letters.

Answer · 3 lettersFirst appearance

EPI

Letters3

Starts withE

Ends withI

Vowels2

Where this clue has appeared

NYT Crossword
Apr 21, 20263 letters→

About this clue

The clue “Prefix with center” ran in the NYT Crossword on April 21, 2026 as 3-Down. Its answer is a 3-letter word that starts with E and ends with I.

See every answer from the puzzle on the NYT Crossword page for April 21, 2026, or learn how clues like this work in our guide to crossword clue types.

More clues from this puzzle

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FAQ

What is the answer to the “Prefix with center” clue?+

The answer is EPI (3 letters), from the NYT Crossword of April 21, 2026.

Where has this clue appeared?+

We have seen it 1 time in the NYT Crossword.

How do I find other NYT Crossword answers?+

Open the full list of answers for April 21, 2026, or browse every date on the NYT Crossword hub.