Crossword clue

“Ciudad del ___, Paraguay's second-largest city”

This clue appeared as 49-Down in the NYT Crossword on Friday, November 6, 2026. The answer has 4 letters.

Answer · 4 lettersFirst appearance
ESTE
Letters4
Starts withE
Ends withE
Vowels2

Where this clue has appeared

About this clue

The clue “Ciudad del ___, Paraguay's second-largest city” ran in the NYT Crossword on November 6, 2026 as 49-Down. Its answer is a 4-letter word that starts with E and ends with E.

See every answer from the puzzle on the NYT Crossword page for November 6, 2026, or learn how clues like this work in our guide to crossword clue types.

More clues from this puzzle

FAQ

What is the answer to the “Ciudad del ___, Paraguay's second-largest city” clue?+

The answer is ESTE (4 letters), from the NYT Crossword of November 6, 2026.

Where has this clue appeared?+

We have seen it 1 time in the NYT Crossword.

How do I find other NYT Crossword answers?+

Open the full list of answers for November 6, 2026, or browse every date on the NYT Crossword hub.