Crossword clue
“Analgesic agent”
This clue appeared as 46-Down in the NYT Crossword on Thursday, October 22, 2026. The answer has 6 letters.
Answer · 6 lettersFirst appearance
OPIATELetters6
Starts withO
Ends withE
Vowels4
Where this clue has appeared
About this clue
The clue “Analgesic agent” ran in the NYT Crossword on October 22, 2026 as 46-Down. Its answer is a 6-letter word that starts with O and ends with E, with 4 vowels, which often points to a phrase, a name or a borrowed word.
See every answer from the puzzle on the NYT Crossword page for October 22, 2026, or learn how clues like this work in our guide to crossword clue types.
More clues from this puzzle
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FAQ
What is the answer to the “Analgesic agent” clue?+
The answer is OPIATE (6 letters), from the NYT Crossword of October 22, 2026.
Where has this clue appeared?+
We have seen it 1 time in the NYT Crossword.
How do I find other NYT Crossword answers?+
Open the full list of answers for October 22, 2026, or browse every date on the NYT Crossword hub.