Crossword clue

“Anesthetic first used on a patient in 1842”

This clue appeared as 109-Across in the NYT Crossword on Sunday, September 7, 2025. The answer has 5 letters.

Answer · 5 lettersFirst appearance

ETHER

Letters5

Starts withE

Ends withR

Vowels2

Where this clue has appeared

NYT Crossword
Sep 7, 20255 letters→

About this clue

The clue “Anesthetic first used on a patient in 1842” ran in the NYT Crossword on September 7, 2025 as 109-Across. Its answer is a 5-letter word that starts with E and ends with R.

See every answer from the puzzle on the NYT Crossword page for September 7, 2025, or learn how clues like this work in our guide to crossword clue types.

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FAQ

What is the answer to the “Anesthetic first used on a patient in 1842” clue?+

The answer is ETHER (5 letters), from the NYT Crossword of September 7, 2025.

Where has this clue appeared?+

We have seen it 1 time in the NYT Crossword.

How do I find other NYT Crossword answers?+

Open the full list of answers for September 7, 2025, or browse every date on the NYT Crossword hub.