Crossword clue

“Hardest substance in the human body”

This clue appeared as 47-Across in the NYT Crossword on Tuesday, September 8, 2026. The answer has 6 letters.

Answer · 6 lettersFirst appearance
ENAMEL
Letters6
Starts withE
Ends withL
Vowels3

Where this clue has appeared

NYT Crossword
Sep 8, 20266 letters→

About this clue

The clue “Hardest substance in the human body” ran in the NYT Crossword on September 8, 2026 as 47-Across. Its answer is a 6-letter word that starts with E and ends with L, with 3 vowels, which often points to a phrase, a name or a borrowed word.

See every answer from the puzzle on the NYT Crossword page for September 8, 2026, or learn how clues like this work in our guide to crossword clue types.

More clues from this puzzle

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FAQ

What is the answer to the “Hardest substance in the human body” clue?+

The answer is ENAMEL (6 letters), from the NYT Crossword of September 8, 2026.

Where has this clue appeared?+

We have seen it 1 time in the NYT Crossword.

How do I find other NYT Crossword answers?+

Open the full list of answers for September 8, 2026, or browse every date on the NYT Crossword hub.